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The endocannabinoid system in rat gliosomes and its role in the modulation of glutamate release

✍ Scribed by Monica Bari; Tiziana Bonifacino; Marco Milanese; Paola Spagnuolo; Simona Zappettini; Natalia Battista; Francesco Giribaldi; Cesare Usai; Giambattista Bonanno; Mauro Maccarrone


Publisher
Springer
Year
2010
Tongue
English
Weight
542 KB
Volume
68
Category
Article
ISSN
1420-682X

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Rat brain cortex slices were used to study (1) the release of 5-hydroxytryptamine (5-HT) induced by activation of N-methyl-D-aspartate (NMDA) or non-NMDA receptors and (2) the alpha 2-adrenoceptor-mediated modulation of NMDA-evoked 5-HT release. Cortical slices were preincubated with [3H]5-HT in the