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The emerging pathogenic and therapeutic importance of the anaplastic lymphoma kinase gene

โœ Scribed by Fergal C. Kelleher; Ray McDermott


Book ID
116430393
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
329 KB
Volume
46
Category
Article
ISSN
0959-8049

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โœ Willy G. Dirks; Silke Fรคhnrich; Yvonne Lis; Elisabeth Becker; Roderick A.F. MacL ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 378 KB

## Abstract The initial identification of the __ALK__ gene, expressed as Cโ€terminal part of the transforming fusion protein NPMโ€ALK in the t(2;5)(p23;q35) lymphomaโ€associated chromosomal translocation, revealed a novel receptor tyrosine kinase (RTK). In order to expand the knowledge on __ALK__ expr