The emergence of nitroxyl (HNO) as a pharmacological agent
β Scribed by Christopher H. Switzer; Wilmarie Flores-Santana; Daniele Mancardi; Sonia Donzelli; Debashree Basudhar; Lisa A. Ridnour; Katrina M. Miranda; Jon M. Fukuto; Nazareno Paolocci; David A. Wink
- Book ID
- 113484427
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 307 KB
- Volume
- 1787
- Category
- Article
- ISSN
- 0005-2728
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π SIMILAR VOLUMES
## Abstract In this study, we report the synthesis and the evaluation as MRI contrast agent of a new compound (nitroxyl fatty acid, NFA), where a pyrrolidinoxyl radical (3βcarboxyβproxyl, PCA) is linked to a fatty acid moiety. Fatty acids were selected as vector because they present a high affinity
The excited states of the HNO radical slave been studied using the equations of motion method. These ulcuktions confirm the presence of a low-lying 'A" state at 5485 cm", which lies between the 'A' ground state and [A" excited state..