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The emergence of nitroxyl (HNO) as a pharmacological agent

✍ Scribed by Christopher H. Switzer; Wilmarie Flores-Santana; Daniele Mancardi; Sonia Donzelli; Debashree Basudhar; Lisa A. Ridnour; Katrina M. Miranda; Jon M. Fukuto; Nazareno Paolocci; David A. Wink


Book ID
113484427
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
307 KB
Volume
1787
Category
Article
ISSN
0005-2728

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Evaluation of a nitroxyl fatty acid as l
✍ Bernard Gallez; RenΓ© Debuyst; Roger Demeure; Fernand Dejehet; CΓ©cile Grandin; Be πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 911 KB

## Abstract In this study, we report the synthesis and the evaluation as MRI contrast agent of a new compound (nitroxyl fatty acid, NFA), where a pyrrolidinoxyl radical (3‐carboxy‐proxyl, PCA) is linked to a fatty acid moiety. Fatty acids were selected as vector because they present a high affinity