Stargardt's disease-fundus flavimaculatus has four general distribution patterns in fundus appearance: (1) macular degeneration without flecks; (2) macular degeneration with perifoveal flecks; (3) macular degeneration with diffuse flecks; and (4) diffuse flecks without macular degeneration (Noble an
The electroretinogram in Stargardt's disease and fundus flavimaculatus
โ Scribed by Pierre Lachapelle; John M. Little; Marie Sylvie Roy
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 716 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0012-4486
No coin nor oath required. For personal study only.
โฆ Synopsis
A retrospective study was performed comparing the ERG results of 15 patients with Stargardt's disease and fundus flavimaculatus. Patients with fundus flavimaculatus had "fishtail" lesions with or without macular changes, while the Stargardt's group had macular atrophy without fish-tail flecks. The mean visual acuity was 20/200 for the Stargardt's patients compared with a mean of 20/80 for the fundus flavimaculatus patients. The Stargardt's photopic and scotopic amplitudes were respectively 33 % and 34% of normal, while the fundus flavimaculatus values were less impaired at 58% and 64% of normal.
๐ SIMILAR VOLUMES
An unusual asymmetric pattern of fundus flavimaculatus was observed in a unilateral myopic patient. Although electrophysiologic testing was similar for both eyes, fundus lesions were different and less pronounced in the myopic eye.
Dark-adapted electroretinograms were obtained over a 3.6-log range of stimulus intensities from 17 black and 15 white normal subjects. Subjects were grouped on the basis of light or dark fundus pigmentation, determined from digitized fundus photographs. B-wave amplitudes for each group were fitted b
We agree with Dr Jellinger's overall point that several different pathological lesions, alone or in combination, may ac-
A retrospective analysis was performed on the transient and steady-state pattern electroretinograms recorded from 42 patients with glaucoma, 13 patients with senile dementia of the Alzheimer's type, 58 patients with diabetes mellitus, and 92 control subjects to evaluate the pattern of electroretinog