The Electrochemical Behavior of Nitrazepam at a Screen-Printed Carbon Electrode and Its Determination in Beverages by Adsorptive Stripping Voltammetry

✍ Scribed by Natasha D. McGuire; Kevin C. Honeychurch; John P. Hart

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 180 KB
• Volume: 21
• Category: Article
• ISSN: 1040-0397
• DOI: 10.1002/elan.200904667

✦ Synopsis

Abstract

The cyclic voltammetric behavior of nitrazepam was investigated at screen‐printed carbon electrodes over the range −1.5 V to +1.5 V. Two reduction peaks were observable on the negative scan, at −0.7 V, and −1.2 V using pH 6 buffer. On the return scan a single oxidation peak was obtained at −0.05 V. For quantitative analysis of beverages, we developed an anodic adsorptive stripping voltammetric method which required only dilution with buffer. The identification of nitrazepam and flunitrazepam could be achieved using cyclic voltammetry.