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The efficient synthesis of amphiphilic oximes of galactose and glucosamine

✍ Scribed by Janez Mravljak; Aleš Obreza


Book ID
113930648
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
364 KB
Volume
53
Category
Article
ISSN
0040-4039

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✍ Damien Forget; Didier Boturyn; Eric Defrancq; Jean Lhomme; Pascal Dumy 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB 👁 1 views

A convergent strategy for the synthesis of peptide ± oligonucleotide conjugates (POC) is presented. Chemoselective ligation of peptide to oligonucleotide was accomplished by oxime and thiazolidine formation. Oxime conjugation was performed by treating an oxyamine-containing peptide with an aldehyde-