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The efficiency of folding of some proteins is increased by controlled rates of translation in vivo: A hypothesis

โœ Scribed by Ian J. Purvis; Andrew J.E. Bettany; T.Chinnappan Santiago; John R. Coggins; Kenneth Duncan; Robert Eason; Alistair J.P. Brown


Book ID
118066544
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
532 KB
Volume
193
Category
Article
ISSN
0022-2836

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Possible translational pauses within the coat protein of the RNA bacteriophage MS2 were located on the basis of a distribution plot of rare codons and RNA secondary structure. It appeared that the position of certain codon pauses corresponds with the size of some nascent polypeptide intermediates, w