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The efficacy of shortening the dosing interval to once every six weeks in Crohn’s patients losing response to maintenance dose of infliximab

✍ Scribed by U. Kopylov; G. J. Mantzaris; K. H. Katsanos; C. Reenaers; P. Ellul; J. F. Rahier; E. Israeli; P. L. Lakatos; G. Fiorino; M. Cesarini; E. V. Tsianos; E. Louis; S. Ben-Horin

Book ID
108606145
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
198 KB
Volume
33
Category
Article
ISSN
0269-2813

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## Background: Tumor necrosis factor-alpha (tnf-alpha) may contribute to the alterations in protein and energy metabolism present in children with crohn's disease (cd), who frequently suffer from growth disturbance. we hypothesized that anti-tnf-alpha therapy would reduce protein losses, due to dec