The efficacy of catheters coated with minocycline and rifampin in the prevention of catheter-related bacteremia in cancer patients receiving high-dose interleukin-2
โ Scribed by R.F. Chemaly; P.S. Sharma; S. Youssef; D. Gerber; P. Hwu; S.S. Hanmod; Y. Jiang; R.Y. Hachem; I.I. Raad
- Book ID
- 118450818
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 151 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1201-9712
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## Background: The aim of this study was to determine the efficacy of novobiocin and rifampin as oral antibiotic prophylaxis for the prevention of catheter-related infection in melanoma patients treated with interleukin-2 (il-2) plus interferon-alpha and chemotherapy (biochemotherapy). ## Methods:
## BACKGROUND. Administration of recombinant high dose interleukin-2 (IL-2) can mediate tumor regression in patients with metastatic melanoma and renal carcinoma. Significant trends in the safety of high dose IL-2 administration at a single institution over a 12-year study period were reviewed. #