The enhanced sensitivity of the elderly to the side effects produced by tricyclic antidepressants (TCAs), and the frequency and type of adverse events, have made the treatment of depression in this group difficult. The selective serotonin reuptake inhibitors (SSRIs) have been reported to produce sig
The efficacy and tolerability of divalproex sodium in elderly demented patients with behavioral disturbances
โ Scribed by Mark E. Kunik; Lucy Puryear; Claudia A. Orengo; Victor Molinari; Richard H. Workman Jr
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 85 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0885-6230
No coin nor oath required. For personal study only.
โฆ Synopsis
Behavioral disturbances are commonly encountered in elderly demented patients. The records of all patients admitted to a geropsychiatric inpatient unit within a 2-year period who had a primary diagnosis of dementia and an accompanying behavioral disturbance treated with divalproex sodium were reviewed. Of the 13 patients identiยฎed, all tolerated divalproex sodium without signiยฎcant side-eects. General psychiatric symptoms, overall agitation, physical aggression and non-aggressive physical agitation decreased signiยฎcantly, but verbal agitation did not. Divalproex sodium is well tolerated and may be eective in ameliorating certain behavioral disturbances in elderly demented patients with agitation.
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