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The efficacy and relationship between peak concentration and toxicity profile of fixed-dose-rate gemcitabine plus carboplatin in patients with advanced non-small-cell lung cancer

โœ Scribed by Linrun Wang; Xiuhua Wu; Mingzhu Huang; Jie Cai; Nong Xu; Jian Liu


Publisher
Springer
Year
2006
Tongue
English
Weight
234 KB
Volume
60
Category
Article
ISSN
0344-5704

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## BACKGROUND. We performed a Phase 1-11 trial to determine the maximum tolerated dose of carboplatin (CBDCA) with a fixed dose of VP-16 and granulocyte-colony stimulating factor (G-CSF) in small cell lung cancer (SCLC) patients. ## METHODS. Treatment consisted of a starting dose of CBDCA, 400