The Effects of X-Rays on the Progress of L-Cells through the Cell Cycle
β Scribed by S. Mak and J. E. Till
- Book ID
- 124601737
- Publisher
- Bioone
- Year
- 1963
- Tongue
- English
- Weight
- 583 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0033-7587
- DOI
- 10.2307/3571352
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
L-thioproline (thiazolidine-4-carboxylic acid, L-Tp) reduces DNA synthesis in cultured HeLa cells by about 50% when added to synchronized cultures at the beginning of GI phase. This inhibition is not observed when the drug is added at mid-S, in G2 or in M. L-Tp almost annuls the burst in 22Na uptake
## Abstract Cell cycle progression is dependent upon the action of cyclins and their partners the cyclin dependent kinases (CDKs). Each cell cycle phase has its own characteristic cyclinβCDK combination, cyclin DβCDK4,6 and cyclin EβCDK2 being responsible for progression through G~1~βphase into Sβp