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The Effects of Vandetanib on Paclitaxel Tumor Distribution and Antitumor Activity in a Xenograft Model of Human Ovarian Carcinoma

โœ Scribed by Cesca, Marta; Frapolli, Roberta; Berndt, Alexander; Scarlato, Valentina; Richter, Petra; Kosmehl, Hartwig; D'Incalci, Maurizio; Ryan, Anderson J.; Giavazzi, Raffaella


Book ID
122226613
Publisher
Neoplasia Press
Year
2009
Tongue
English
Weight
782 KB
Volume
11
Category
Article
ISSN
1522-8002

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Taxanes such as paclitaxel (Taxol) and docetaxel (Taxotere) are promising agents for use against ovarian cancer and other malignancies. Recently, SB-T-1011, a semisynthetic taxane, has been prepared from 14-hydroxy-10-deacetylbaccatin III. SB-T-1011 shows similar or greater in vitro cytostatic activ