The effects of tumour extract on macrophage proliferation in lymph-nodes
โ Scribed by I. Carr; P. Price; S. Westby
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 207 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0022-3417
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โฆ Synopsis
Injection of a soluble tumour extract induces mitosis in sinus macrophages of the draining lymph-node. This is not abolished by irradiation; the stimulus also induces monocytosis somewhat later. These findings make it likely that the stimulus induces mitosis in the resident lymph-node macrophage population.
๐ SIMILAR VOLUMES
A modified version of the local lymph node assay (LLNA) is presented, using bromodeoxyuridine to label proliferating lymphocytes. Cell counting is done on mid-sagittal sections of individual nodes under light microscopy. Two irritants (sodium lauryl sulfate and salicylic acid), four allergens of var