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The effects of the CDK inhibitor seliciclib alone or in combination with cisplatin in human uterine sarcoma cell lines

✍ Scribed by Helen M. Coley; Christine F. Shotton; Maria I. Kokkinos; Hilary Thomas


Book ID
113960967
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
604 KB
Volume
105
Category
Article
ISSN
0090-8258

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## Abstract Tumor necrosis factor Ξ± (TNF) exhibits cytotoxic activity on some solid tumors and has been reported to be synergistic with topoisomerase‐II‐targeted antineoplastic agents. A wide range of TNF concentrations (from 10 to 10,000 U/ml) was tested in 9 human lung cancer cell lines (5 small‐