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The effects of the anti-cancer drugs, methotrexate and 5-fluorouracil, on cognitive function in mice

✍ Scribed by Gordon Winocur; Janette Vardy; Malcolm A. Binns; Leslie Kerr; Ian Tannock


Book ID
113841104
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
426 KB
Volume
85
Category
Article
ISSN
0091-3057

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Recent in vitro and animal tumor studies suggest that sequential methotrexate (MTX) and 5-fluorouracil (5-FU) may be much more tumoricidal than either drug when used alone or in conventional combinations. Seventeen evaluable female patients with advanced carcinoma of the breast were treated with MTX