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The effects of select neurotoxic chemicals on synaptosomal monoamine uptake and K+-dependent phosphatase

โœ Scribed by BRACKEN, W; SHARMA, R; KLEINSCHUSTER, S

Book ID
123117472
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
504 KB
Volume
1
Category
Article
ISSN
0272-0590

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Rat striatal synaptosomes (Pz-fraction) were subjected to lipoperoxidation by the addition of 120 pM Fe2' and 200 pM ascorbic acid. This preparation (pretreated synaptosomes) was used to investigate the interaction of Pb2+ and Mn2+ on the uptake of tritiated catecholamines, Na+, K+-ATPase activity a