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The effects of rubidium, caesium and quinine on 5-HT-mediated behaviour in rat and mouse—1. Rubidium

✍ Scribed by H. Wang; D.G. Grahame-Smith


Book ID
118956558
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
781 KB
Volume
31
Category
Article
ISSN
0028-3908

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The effects of a 5-HT1receptor ligand is
✍ G. M. Goodwin; Rosemarie J. Souza; A. R. Green 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 557 KB

The effects of 2-(4-(4-(2-pyrimidinyl)-l-piperazinyl)-butyl)-1,2-benzoisothiazol-3(2H)one-1,1-dioxide hydrochloride (isapirone, TVX Q 7821), a putative 5-HT1 receptor antagonist, has been studied on various models of 5-HT receptor sub-type function. In mice TVX Q 7821 produced a dose-dependent inhib