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The effects of psychotropic drugs on the double alley frustration effect

✍ Scribed by P. E. Freedman; Alexander J. Rosen

Publisher: Springer
Year: 1969
Tongue: English
Weight: 482 KB
Volume: 15
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00410799

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✦ Synopsis

Central nervous system stimulants (amphetamine, methylphenidate), depressants (sodium amobarbital, reserpine, tetrabenezine, chlorpromazine) and anti-depressants (iproniazid, pargyline) were administered intraperitoneally to rats prior to their daily trials in an Amsel double runway in an attempt to modify the frustration effect using within-subject comparisons. Absolute running speeds following reinforcement and nonreinforcement were markedly affected by the drugs. However, in contradistinction to conditioned frustration which has proven amenable to pharmacological intervention, the primary frustration in the present paradigm, involving a response that immediately follows nonreward, proved highly resistant to modification.

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