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The effects of prostaglandin A2 on cell growth, cell cycle status and apoptosis induction in HeLa and MCF-7 cells

✍ Scribed by Annie M. Joubert; Annie Panzer; Pepita C. Bianchi; Mona-Liza Lottering

Book ID: 117467622
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 289 KB
Volume: 191
Category: Article
ISSN: 0304-3835
DOI: 10.1016/s0304-3835(02)00625-0

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## Abstract We investigated the in vitro effects of pyrogallol on cell growth, cell cycle regulation, and apoptosis in HeLa cells. Pyrogallol inhibited the growth of HeLa cells with an IC~50~ of approximately 45 µM. Pyrogallol induced arrest during all phases of the cell cycle and also very efficie