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The effects of neurokinin A, neurokinin B, and eledoisin on substance P analysis

✍ Scribed by Rebecca J. Naukam; Winston C. V. Parris; J. R. Kambam; Jonathan B. Kruskal

Publisher
Springer
Year
1991
Tongue
English
Weight
450 KB
Volume
7
Category
Article
ISSN
0748-1977

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Substance P (SP) acts as a neurotransmitter in the neostriatum through the axon collaterals of spiny projection neurons. However, possible direct or indirect actions of SP on the neostriatal output neurons have not been described. Targets of SP terminals within the neostriatum include interneurons,

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In situ hybridization histochemistry was used to map the distribution of neurons expressing the substance P (SP) or neurokinin B (NKB) genes in the human hypothalamus and basal forebrain. Hypothalami from five adult males were frozen in isopentane at 230Β°C and serially sectioned at 20 Β΅m thickness.