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The effects of nasal irritant induced responses on breathing and cough in anaesthetized and conscious animal models

✍ Scribed by Biringerova, Z.; Gavliakova, S.; Brozmanova, M.; Tatar, M.; Hanuskova, E.; Poliacek, I.; Plevkova, J.


Book ID
122368933
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
510 KB
Volume
189
Category
Article
ISSN
1569-9048

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Desethylamiodarone (DEA), the mjor active metabolite of amiodarone (AMD), plays a significant role in the electrophysiological effects observed during AMD thexapy. The pharmacokinetics and pharmacodynamics of DEA wcre studied in rats. Animals were administered DEA (20 or 40 mg kg-I) and blood sample