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The Effects of Multiple Doses of Ivermectin on Ocular Onchocerciasis

โœ Scribed by Mabey, Denise; Whitworth, James A.; Eckstein, Michael; Gilbert, Clare; Maude, Gillian; Downham, Michael

Book ID
123202134
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
809 KB
Volume
103
Category
Article
ISSN
0161-6420

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The effects of high-dose ivermectin regi
The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients
โœ Kwablah Awadzi; Simon Kwaku Attah; Ebenezer Thomas Addy; Nicholas Obuobisa Opoku ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 630 KB

Ivermectin, at the standard dose of 150 cLg/kg bodyweight, does not kill the adult worms of Onchocerca volvulus and does not disrupt embryogenesis or spermatogenesis. Repeated standard doses, if maintained, arrest microfilarial production but result in only a mild-to-modest macrofilaricidal effect.