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The effects of mirtazapine and fluoxetine on hyperthermia induced by 3,4-methylenedioxymethamphetamine (MDMA) in rats

✍ Scribed by Makiko Kasai; Katsutoshi Shioda; Koichi Nisijima; Tatsuki Yoshino; Tatsunori Iwamura; Satoshi Kato

Book ID
116773218
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
404 KB
Volume
499
Category
Article
ISSN
0304-3940

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✍ Vijay V. Upreti; Natalie D. Eddington πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 342 KB

Fluoxetine has been shown to provide protection from MDMA induced long term neurotoxicity. The purpose of this investigation is to evaluate the pharmacokinetic drug interaction between MDMA and fluoxetine and also to determine the role of P-glycoprotein (P-gp) on mediating drug-drug interactions wit