The effects of litter size during gestation and lactation on rat development prior to weaning
✍ Scribed by Dr. Francine Wehmer; Kai-Lin Catherine Jen
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 464 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0012-1630
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Physiological and behavioral development of rats was affected by prenatal nutrition and postnatal litter size. Prenatal nutrition was manipulated by combining differences in maternal nutrition with variation of prenatal litter size produced by pre‐mating isolation of 1 uterine horn. The pups were reared in postnatal litters of either 4 or 12. During the 1st postnatal week, development and free behavior were affected only by the prenatal treatments. During the 2nd postnatal week, both prenatal and postnatal effects were observed. Development and behavior during the 3rd postnatal week reflected only postnatal litter size. Brain weight at weaning was influenced by both the prenatal and postnatal treatments.