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The effects of levodopa and ongoing deep brain stimulation on subthalamic beta oscillations in Parkinson's disease

✍ Scribed by Gaia Giannicola; Sara Marceglia; Lorenzo Rossi; Simona Mrakic-Sposta; Paolo Rampini; Filippo Tamma; Filippo Cogiamanian; Sergio Barbieri; Alberto Priori


Book ID
118441393
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
790 KB
Volume
226
Category
Article
ISSN
0014-4886

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Cardinal symptoms of Parkinson's disease (PD) respond well to treatment with levodopa and deep brain stimulation (DBS) of the subthalamic nucleus (STN). However, it has remained unclear whether levodopa and STN-DBS have differential effects on bradykinesia. We investigated 8 PD-patients with STN-ele

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## Abstract Patients with Parkinson's disease (PD) show impairment in generating random motor sequences reflecting a higher order motor deficit in set‐shifting and suppression of perseverative behavior. The impact of deep brain stimulation (DBS) of the subthalamic nucleus (STN) on motor perseverati