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The effects of kynurenic acid, quinolinic acid and other metabolites of tryptophan on the development of the high pressure neurological syndrome in the rat

✍ Scribed by Bridget Wardley-Smith; M.J. Halsey; Diane Hawley; M.H. Joseph

Book ID
118956081
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
655 KB
Volume
28
Category
Article
ISSN
0028-3908

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Effects of kynurenic acid on amygdaloid
Effects of kynurenic acid on amygdaloid kindling in the rat
✍ James L Thompson; Gregory L Holmes; Gregory W Taylor; Daniel R Feldman πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 English βš– 756 KB

The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy. Treatment with intracerebroventricular KYA (360 nmoles (adult dose) or 240 nmoles (prepuhescent dose))