The effects of infliximab therapy on the serum proteome of rheumatoid arthritis patients
✍ Scribed by Ravi C Dwivedi, Navjot Dhindsa, Oleg V Krokhin…
- Book ID
- 120706793
- Publisher
- BioMed Central
- Year
- 2009
- Tongue
- English
- Weight
- 829 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1478-6354
- DOI
- 10.1186/ar2637
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## Abstract ## Objective According to the Centers for Disease Control and Prevention, the 1999 and 2000 incidence rates for tuberculosis (TB) in the US population were 6.4 and 5.8, respectively, per 100,000 persons. Recently, reports of TB following infliximab administration have raised questions
In patients with rheumatoid arthritis (RA) a decrease in the terminal galactose content of N-linked glycans of the Fc region of agalactosyl immunoglobulin G (IgG) (G0) occurs. The aim of this study was to evaluate, for the first time, the effect of infliximab, a new monoclonal antibody for the treat