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The effects of immunoglobulin isotype and antibody affinity on complement-mediated inhibition of immune precipitation and solubilization

✍ Scribed by Ann Johnson; Susannah Harkin; M.W. Steward; K. Whaley


Book ID
119089760
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
735 KB
Volume
24
Category
Article
ISSN
0161-5890

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Inhibitory effect of igm rheumatoid fact
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Purified IgM rheumatoid factors (RF; 3 monoclonal and 2 polyclonal) were shown to inhibit, in a dosedependent manner, 2 complement-mediated functions, Le,, the immune complex solubilization capacity and the inhibition of immune precipitation. Inhibition of immune complex solubilization capacity occu