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The effects of ifenprodil on the activity of antidepressant drugs in the forced swim test in mice

✍ Scribed by Poleszak, Ewa; Wośko, Sylwia; Serefko, Anna; Wlaź, Aleksandra; Kasperek, Regina; Dudka, Jarosław; Wróbel, Andrzej; Nowak, Gabriel; Wlaź, Piotr


Book ID
127326737
Publisher
Elsevier
Year
2014
Tongue
English
Weight
335 KB
Volume
66
Category
Article
ISSN
1734-1140

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The influence of naloxone on the effects of several antidepressant drugs, atropine and caffeine was studied in the forced swimming test in mice. Naloxone itself has no effect in this test, but significantly reduces that of two tricyclic antidepressants, clomipramine (20 and 30 mg/kg) and desipramine