Cytosolic calcium plays a crucial role as a second messenger in cellular signalling. Various cell types, including hepatocytes, display Ca> oscillations when stimulated by an extracellular signal. However, the biological relevance of this temporal organization remains unclear. In this paper, we inve
The Effects of hydrocortisone on glycogen storage and phosphorylase activity of frog liver
β Scribed by Hunter, Norvell W. ;Johnson, Charles E.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1960
- Tongue
- English
- Weight
- 435 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0095-9898
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π SIMILAR VOLUMES
Allosteric enzymes have very complex kinetic behaviours which are primarily interpreted through simplified models. To describe the functional properties of liver and muscle glycogen phosphorylase isozymes we have developed an experimental strategy based on the measurements of initial reaction rates
## Abstract Selfβassociation of phosphorylase kinase (PhK) and its interaction with glycogen (__M__=5500βkDa) and phosphorylase __b__ (Ph__b__) has been studied using analytical ultracentrifugation and turbidimetry under the conditions of molecular crowding arising from the presence of high concent
The glucose-induced switch between glycogen phosphorylase and glycogen synthase in the liver is investigated by means of a theoretical approach based on a minimal, bicyclic cascade model involving the reversible phosphorylation of the two enzymes. The aim of the analysis is to evaluate the contribut