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The effects of horseradish peroxidase on the concentration of 5-hydroxytryptamine and platelet counts in blood of rabbits and guinea pigs

✍ Scribed by R. Haye; Ø. V. Sjaastad; A. K. Blom; T. Vegge

Publisher
Springer
Year
1978
Tongue
English
Weight
780 KB
Volume
58
Category
Article
ISSN
1432-119X

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✦ Synopsis

When HRP was injected i.v. in rabbits and guinea pigs, a rapid fall in the number of circulating platelets and the concentration of 5 HT occurred. Platelet aggregates were trapped in lung capillaries. The aggregation was reversible and the return of platelets to the circulation concomitant with a rise in blood 5 HT concentration.

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