The effects of homocysteine and homocysteic acid on the metabotropic glutamate receptors of cerebellar neurons
โ Scribed by I. A. Sergeeva; A. V. Makhro; A. N. Pegova; E. R. Bulygina
- Book ID
- 111470655
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2010
- Tongue
- English
- Weight
- 129 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1819-7124
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The cellular and subcellular localization of the mGluR5 metabotropic glutamate receptor subtype was studied in the rat cerebellar cortex, by using the preembedding immunoperoxidase and immunogold techniques. Light microscopic observations revealed an abundant, intense labeling of neurons in the gra
## Abstract Increased serum level of homocysteine, a sulfurโcontaining amino acid, is considered a risk factor in vascular disorders and in dementias. The effect of homocysteine and metabolically related compounds on brain production of kynurenic acid (KYNA), an endogenous antagonist of glutamate i