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The effects of estrogen and progesterone on prostaglandins and integrin beta 3 (β3) subunit expression in primary cultures of bovine endometrial cells

✍ Scribed by Sarah Kimmins; Hai Choo Lim; Julie Parent; Michel A. Fortier; Leslie A. MacLaren


Book ID
117565322
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
350 KB
Volume
25
Category
Article
ISSN
0739-7240

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## Abstract Optimal stimulation of signal transduction and biological functions by IGF‐I in porcine smooth muscle cells (pSMC) requires ligand occupancy of the αVβ3 integrin. Binding of heparin‐binding domain (HBD) of vitronectin (VN) to the cysteine loop (C‐loop) region of β3 is required for pSMC