Clinical recovery, cognitive function, and ward behavior indicative of organic brain syndrome were assessed in 12 elderly, depressed patients before, and approximately one week after, treatment with electroconvulsive therapy (ECT). There was a statistically significant improvement in depression, and
The effects of ECT on cognitive functioning in the elderly: a review
✍ Scribed by Caroline E. M. Tielkes; Hannie C. Comijs; Esmée Verwijk; Max L. Stek
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 74 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0885-6230
- DOI
- 10.1002/gps.1989
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background
Electroconvulsive therapy (ECT) as a single course or in maintenance form (M‐ECT) is an effective treatment in depressed elderly. However, ECT may have adverse effects on cognition.
Objective
To review all studies from 1980–2006 on ECT and cognition in the elderly with a minimum age of 55 years or a mean age of 55 years, and with valid measurements of cognition before and after ECT.
Results
Nine out of the 15 eligible studies were focused exclusively on the elderly. Three studies reported verbal learning‐ and recall problems post ECT, while three studies found positive effects of ECT on memory, speed of processing and concentration. Global cognitive functioning in patients with cognitive impairment improved in all studies. At follow up, most studies reported improvement of cognitive functions. Learning verbal information and executive functioning were impaired in M‐ECT patients whereas global cognition remained stable after M‐ECT over a year.
Conclusions
To date research of ECT on cognitive functioning in the elderly is very limited. Small sample size, lack of controls, use of a single screening instrument and a short follow up period may explain the conflicting results. Given the clinical importance, more extensive research on cognition in elderly treated with ECT is urgently needed. Copyright © 2008 John Wiley & Sons, Ltd.
📜 SIMILAR VOLUMES
## Abstract ## Objective Benzodiazepines (BZDs) have been reported to cause negative impacts on body stability and cognitive functions, which in turn could result in lethal incidents, including falls, especially in the elderly. This fact notwithstanding, no systematic trial has evaluated the feasi
## Abstract ## Background The public health impact of cognitive decline and dementia is increasing as the population ages. Studies exploring therapies or risk factors for cognitive impairment require understanding of expected age‐related decline. ## Objective To establish the rate of age‐related
## SUMMARY Cognitive impairment has emerged as a major driver of disability in old age, with profound effects on individual well‐being and decision making at older ages. In the light of policies aimed at postponing retirement ages, an important question is whether continued labour supply helps to m
Sixty-six elderly depressed patients received fluoxetine 20 mg (FLU) or amitriptyline 75 mg (AMI) for 42 days in a double blind parallel group study. Each week, subjects completed a test battery which is sensitive to the residual effects of psychoactive drugs. The results show that FLU and AM1 were