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The effects of CD59 gene as a target gene on breast cancer cells

✍ Scribed by Bing Li; Xianming Chu; Meihua Gao; Yingjie Xu

Book ID
113527488
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
979 KB
Volume
272
Category
Article
ISSN
0008-8749

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## Abstract The amplification of the q21 band of chromosome 8 (8q21) occurs in a large percentage of breast cancers. WWP1, an HECT domain‐containing ubiquitin E3 ligase located in the 8q21 region, negatively regulates the TGF‐β tumor suppressor pathway. To characterize the role of __WWP1__ in breas