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The effects of cardiopulmonary bypass on plasma concentrations and protein binding of methohexital and thiopental

✍ Scribed by Bjorksten, Andrew R.; Crankshaw, David P.; Morgan, Denis J.; Prideaux, Peter R.

Book ID
122469215
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
807 KB
Volume
2
Category
Article
ISSN
0888-6296

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## Abstract Following thiopental injection to rabbits in doses of 5 mg kg^βˆ’1^ intravenously (i.v.) the sleeping time lasted longer after injection by bolus than after administration made more slowly over 30 or 60 s, respectively. Peak concentration in the blood of the animals after bolus injection