The Effects of Caloric Restriction on Health and Longevity
β Scribed by Jacqueline L. Green; Fadi J. Sawaya; Allen L. Dollar
- Book ID
- 107556021
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 123 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1092-8464
No coin nor oath required. For personal study only.
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## Abstract Caloric restriction (CR), which improves health and increases longevity, was studied as a therapy in a hexosaminidase Ξ² knockout mouse model of Sandhoff disease (SD), an incurable neurodegenerative disease involving accumulation of brain ganglioside GM2 and asialoβGM2 (GA2). Adult mice
## Abstract Research on caloric restriction for longevity (CRL) has generated hundreds of articles on the physiology of food deprivation, yet almost no data on consequences in other domains. The first paper in this series outlined the generally positive physical effects of CRL; the second analyses