To examine the effect of alendronate (4-amino-1-hydroxybutylidene bisphosphonate) on fracture repair, the drug was given to mature beagle dogs orogastrically at 2 mg/kg/day for 9 weeks preceding fracture. 16 weeks after fracture, or both before and after fracture (25 weeks). A transverse mid-diaphys
The effects of bisphosphonates on jaw bone remodeling, tissue properties, and extraction healing
β Scribed by Matthew R. Allen
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 618 KB
- Volume
- 99
- Category
- Article
- ISSN
- 1618-1247
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Periprosthetic osteolysis and aseptic loosening of total joint replacements are believed to be initiated often by abnormal bone resorption induced by prosthetic wear debris. Bisphosphonates can inhibit bone resorption and have been successfully used clinically to treat osteoporosis and Paget's disea
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