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The effects of benzodiazepines on the behaviour of mice on a hole-board

✍ Scribed by Norma A. Nolan; M. W. Parkes

Publisher: Springer
Year: 1973
Tongue: English
Weight: 603 KB
Volume: 29
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00414043

No coin nor oath required. For personal study only.

✦ Synopsis

The effect of exposing mice to a hole-board in reducing the number of head dips made on a subsequent exposure was studied. The period of first exposure that was effective in causing this reduction, the interval between exposure that must elapse before this effect appears and the duration of the effect were also determined. Chlordiazepoxide and other benzodiazepine tranquillizers, given before initial exposure, increased activity in small doses but had little effect upon subsequent activity. They did not affect characteristics of familiarization beyond possibly a slight shortening of the latent period.

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