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The effects of benzodiazepine receptor (BZR) antagonist and BZR inverse agonist on acute hepatic encephalopathy (HE) in the rat

✍ Scribed by Bosman, DK; Maas, MAW; van den Buijs, CACG; Chamuleau, RAFM


Book ID
123383419
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
43 KB
Volume
9
Category
Article
ISSN
0168-8278

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✍ Petra Steindl; Andreas PΓΌspΓΆk; Wilfred Druml; Peter Ferenci πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 605 KB

Hepatic encephalopathy is ameliorated by drugs acting on the central GABA,-benzodiazepine receptor complex. To investigate whether these effects are specific for hepatic encephalopathy or just reflect a nonspecific aroa~al reaction, various benzodiazepine antagonists like flumazenil or with inverse