The effects of antineoplastic agents of the respiratory activity of murine lymphocytic leukemia L1210
β Scribed by M. T. Goodman; G. A. Ackerman
- Book ID
- 112658372
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 544 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1420-682X
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π SIMILAR VOLUMES
## Abstract A glycoprotein extract prepared from the plasma membranes of L1210 cells was passed over columns of Sepharose 4B to which either heatβaggregated human IgG or F(abβ²)~2~ fragments had been coupled. The intact IgG column bound 35.7% of the applied counts, whereas the F(abβ²)~2~ columns boun
The L1210 tumor system was used in vitro and in vivo in comparative studies with activated cyclophosphamide analogs, cyclophosphamide and phosphoramide mustard. All the above compounds gave substantial cell kills (5 logs) of L1210 in vivo at doses that were non-toxic, but slight differences were not