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The effects of an orally administered cholinergic agonist on REM sleep in major depression

✍ Scribed by Michael L Perlis; Michael T Smith; Henry J Orff; Patrick J Andrews; J.Christian Gillin; Donna E Giles

Book ID
119408691
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
56 KB
Volume
51
Category
Article
ISSN
0006-3223

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Flesinoxan is a highly potent and selective 5-HTlA full agonist, active in several models of depression. In this pilot open study, flesinoxan (4 mdd) was administered orally for 4 weeks in 16 major depressive, mostly treatmentresistant inpatients exhibiting a score of at least 19 on the Hamilton dep