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The effects of aluminum loading on the renal response to parathyroid hormone in the vitamin D-replete rat

✍ Scribed by Gordon L. Klein; Thomas C. Lee; June E. Bishop; Marie L. Vaccaro; Mat Jongen; Kiyoshi Kurokawa; Jack W. Coburn; Anthony W. Norman


Book ID
113382569
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
374 KB
Volume
36
Category
Article
ISSN
0885-4505

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Rats fed a diet deficient in vitamin D were found t o exhibit a refractory cyclic AMP response of kidney slices to parathyroid hormone and a marked decrease in membrane parathyroid hormone-dependent adenylate cyclase activity. Both the characteristic calcium deficiency (hypocalcemia) and secondary e