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The effects of alanine-substituted conantokin-G and ifenprodil on the human spermine-activated N-methyl-d-aspartate receptor

✍ Scribed by V.W.-W. Tsai; P.R. Dodd; R.J. Lewis


Book ID
116786715
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
322 KB
Volume
130
Category
Article
ISSN
0306-4522

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The effect of potassium depolarization and N-methyl-D-aspartate (NMDA) on the activity of aspartate aminotransferase (AAT; EC 2.6.1.1), an enzyme suggested to be involved in neurotransmitter glutamate synthesis, was studied in cultured cerebellar granule neurons. Both KCI and NMDA increased AAT acti