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The Effects of Age, Sex, Race, and Weight on the Rate of Intervertebral Disc Degeneration

✍ Scribed by Krzysztof Siemionow; Howard An; Koichi Masuda; Gunnar Andersson; Gabriella Cs-Szabo

Book ID
119372416
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
46 KB
Volume
10
Category
Article
ISSN
1529-9430

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## Abstract A significant biochemical change that takes place in intervertebral disc degeneration is the loss of proteoglycans in the nucleus pulposus. Proteoglycans attract fluid, which works to reduce mechanical stresses in the solid matrix of the nucleus and provide a hydrostatic pressure to the