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The effects of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on T-cell-related cytokine production in vitro and in vivo

โœ Scribed by Satoshi Yamamoto; Shingo Sugahara; Ryo Naito; Atsushi Ichikawa; Ken Ikeda; Toshimitsu Yamada; Yasuaki Shimizu


Book ID
113586203
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
356 KB
Volume
541
Category
Article
ISSN
0014-2999

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## Abstract The ECRG4 gene was initially identified and cloned in our laboratory from human normal esophageal epithelium (GenBank accession no. AF325503). We revealed the expression of ECRG4 protein was downregulated in 68.5% (89/130) ESCC samples using tissue microarray. The low ECRG4 protein expr