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The effects of a low vitamin E diet on dichloroacetate- and trichloroacetate-induced oxidative stress in the livers of mice

✍ Scribed by Jacquelyn Cearfoss; Ezdihar Hassoun


Book ID
112119606
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
238 KB
Volume
26
Category
Article
ISSN
1095-6670

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πŸ“œ SIMILAR VOLUMES


Dichloroacetate- and trichloroacetate-in
✍ Ezdihar A. Hassoun; Jacquelyn Cearfoss; Jessica Spildener πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 331 KB

## Abstract Dichoroacetate (DCA) and trichloroacetate (TCA) were found to be hepatotoxic and hepatocarcinogenic in rodents. To investigate the role of oxidative stress in the long‐term hepatotoxicity of the compounds, groups of mice were administered 7.7, 77, 154 and 410 mg kg^βˆ’1^ per day, of eithe

Dichloroacetate- and trichloroacetate-in
✍ Ezdihar A. Hassoun; Soumyadeep Dey πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 225 KB

## Abstract Dichoroacetate (DCA) and trichloroacetate (TCA) are by‐products formed during chlorination of the drinking water and were found to be hepatotoxic and hepatocarcinogenic in rodents. In this study, the abilities of the compounds to induce oxidative stress and phagocytic activation have be