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The effects of 1-nitropyrene, 2-amino-1-methyl-6-phenylimidazo[4,5–b]pyridine and 7,12-dimethylbenz[a]anthracene on 8-hydroxy-2′-deoxyguanosine levels in the rat mammary gland and modulation by dietary 1,4-phenylenebis(methylene)selenocyanate

✍ Scribed by Karam El-Bayoumy; Young-Heum Chae; José G Rosa; LeeAnn K Williams; Dhimant Desai; Shantu Amin; Emerich Fiala

Book ID
117469744
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
167 KB
Volume
151
Category
Article
ISSN
0304-3835

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✍ Sarah J. Roberts-Thomson; Elizabeth G. Snyderwine 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB 👁 1 views

Activating mutations in and expression of the Ha-ras gene were examined in benign and malignant female Sprague-Dawley rat mammary gland tumors induced by the heterocyclic amine 2-amino-1-methyl-6phenylimidazo[4,5-b]pyridine (PhIP) and promoted by a diet high in polyunsaturated fat. Ha-ras mutations