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The effectiveness of treating juvenile dermatomyositis with methotrexate and aggressively tapered corticosteroids

✍ Scribed by A. V. Ramanan; N. Campbell-Webster; S. Ota; S. Parker; D. Tran; P. N. Tyrrell; B. Cameron; L. Spiegel; R. Schneider; R. M. Laxer; E. D. Silverman; B. M. Feldman


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
143 KB
Volume
52
Category
Article
ISSN
0004-3591

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✍ Ann-Kristin Ulfgren; Cecilia Grundtman; Kristian Borg; Helene Alexanderson; Ulf πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 318 KB πŸ‘ 2 views

## Abstract ## Objective High mobility group box chromosomal protein 1 (HMGB‐1) is an endogenous nuclear protein that can be translocated to the cytoplasm and then released extracellularly. It can induce tumor necrosis factor and interleukin‐1 production in myeloid cells. Increased expression of t